- Simpkins, D.C.2
- Sims, John, 1790-18682
- Smith, G. D., b. 18212
- Smith, Simmie H.2
- Smyth, James2
- South Carolina Council on Human Relations2
- South Carolina Department of Health and Environmental Control, Bureau of Air Quality2
- South Carolina Department of Natural Resources2
- South Carolina Education Oversight Committee2
- South Carolina State Department of Education2
- South Carolina. State Election Commission2
- Southern Bell Telephone and Telegraph Company2
- Suber, Christian Henry, Quartermaster, 1828-18902
- Superior Postcard Co.2
- Thomas, Heber2
- Troughton & Simms, London2
- United States. Dept. of Agriculture. Commodity Stabilization Service2
- Verdier, Simeon (Simon), 1780-18532
- WIS-TV (Producer)2
- Waccamaw Council 2