- Sims, Chester1
- Sims, Henry R.1
- Sims, J. Marion (James Marion) 1813-18831
- Sims, J. S.1
- Sims, James1
- Sims, James T.1
- Sims, Jimmie, 1922-2011 (interviewee)1
- Sims, Newton1
- Sims, Reba1
- Sims, Reuben T.1
- Simson, Archibald, 1564-16281
- Smedley's Hydro Co. Limited, Matlock Bank1
- Smith, G.D.,1821-1
- Smith, Ira T.1
- Solomon, Ted1
- South Carolina Aeronautics Commission1
- South Carolina Board of Nursing1
- South Carolina Department of Health and Environmental Control, Air Permitting Division1
- South Carolina Department of Health and Environmental Control, Bureau of Air Quality, Engineering Services Division1
- South Carolina Educational Television Commission1