- Kimble, Prince H. B.1
- Kinard, Michael Middleton, 1856-19241
- Lehrè, Thomas1
- Lewis, T. R.1
- Lowndes, Sallie1
- Lucas Family1
- Lynch, Sabina, 1747-18121
- M.L. Corley & Sons1
- Manigault, Charles Izard, 1795-18741
- Manigault, Charlotte 1792-18191
- Martin, Louis1
- Mayes, Vern1
- McGown-Silsby Lithography Company1
- McRant, Josephine A.1
- Medical College of South Carolina1
- Michel, William Middleton1
- Mickey, J. K.1
- Middleton & Montgomery Insurance Agency1
- Middleton Advertising Company1
- Middleton, C.K.1