- Sherman, Joe, 1912-19902
- Shivar Spring Company2
- Signode Corporation2
- Simmons Cruise/Olympia2
- Simons, Jane K.2
- Simpkins, D. C.2
- Simpkins, D.C.2
- Skipper's Studio, Georgetown, South Carolina2
- Sloan, Eugene B.2
- Smith, A.2
- Smith, Alice Ravenel Huger, 1876-19582
- Smith, Charles, 17962
- Smith, Steve (Photographer)2
- Solesbee Studio2
- South Carolina Council on Human Relations2
- South Carolina State Library (Collector)2
- South Carolina. Department of Parks, Recreation, and Tourism2
- South Carolina. State Highway Department2
- Southworth, Ginny (photographer)2
- Spalding, Frances2