- Cator, John S.1
- Chandler, C.L. (Filmmaker)1
- Charles Family1
- Charleston (S.C.) Committee on Artesian Wells1
- Clinton, Henry, 1730-17951
- Coe, Fred, 1914-19791
- Colbert, Charles F.1
- Columbia Lyric Theatre (S.C.)1
- Columbia Opera House (Columbia, S.C.)1
- Columbia Stage Society (Columbia, S.C.)40
- Conlon, M. P.1
- Conner, Henry Calvin, 1835-18831
- Cook, George LaGrange2
- Cooperative Extension Service, Clemson University1
- Creighton, Robert K.1
- Dalcho, Frederick, 1770-18361
- Daniels, Ron D.1
- Dankworth, Frederick, approximately 1804- (Engraver)2
- Davis, Bishop1
- De Fontaine, F. G. (Felix Gregory), 1832-18961