- Esau Jenkins Papers, 1963-2003143
- Mamie E. Garvin Fields Papers, 1894 - 1987120
- Temple Sinai (Sumter, S.C.) Records103
- Butler Derrick: In His Own Words101
- Early History of Columbia College97
- James E. Campbell papers, 1930-200990
- Eugene C. Hunt Papers, 1834 - 199486
- Rabbi Jacob S. Raisin Papers68
- Edmondston-Alston Family Letters and Paper Materials, 1782-191964
- Hunger in America62
- L. Mendel Rivers Papers, 1940-196257
- Hampstead and Bethany Cemeteries53
- Berkeley County (S.C.) Memories52
- Town of Sullivan's Island Historic Meeting Minutes51
- City Year Books for Charleston, South Carolina, 1880-195143
- Clemson University Faculty Manuals38
- M. Hayes Mizell Papers35
- Ethelyn Murray Parker Papers34
- Martha Elizabeth Cunningham Monteith Collection34
- Anna D. Kelly Papers, 1930s - 199933