- UDC South Carolina Chapter13
- History of the University of South Carolina School of Medicine - Columbia12
- Midlands Memories12
- Bratton Family Papers, 1764-1983.11
- Isaiah DeQuincey Newman Papers11
- Philip Simmons Collection11
- B. A. Rodrigues Ottolengui Collection8
- Historical and Governing Records, 1841-19258
- Tri-Daily Meteorological Records, 18788
- Miriam DeCosta Seabrook and Herbert U. Seabrook Papers, 1882-19957
- Charleston Year Book, 19375
- South Carolina Historical Records Survey Collection5
- The Joel Myerson Collection of Nineteenth-Century American Manuscripts, Images, and Ephemera5
- Charleston Year Book, 19384
- Cohen, Emanuel, Moses, Seixas Family Papers4
- Fritz Hollings: In His Own Words4
- Greenville City Codes4
- Illustrated Newspaper Clippings, 1840-19174
- Middleton Papers, 1775-18154
- Phillis Wheatley Literary and Social Club Papers4