- Thomas Jones Davies Bible Records2
- Weston Family Papers, 1764-18552
- William Moultrie Correspondence, 17812
- 2nd South Carolina Regiment Order Book and Related Records, 1777-ca. 19291
- 72/74 Tradd Street Ownership History Scrapbook1
- Abby D. Munro Papers, 1869-19261
- Advertisement for Madame Togno's School for Young Ladies, ca. 18551
- Agatha Aimar Simmons Papers, 1903-19621
- Agricultural Experiments and South Mulberry Plantation Journal, 1841-1907 (bulk 1841-1867)1
- Alexander Glennie Journal, 1831-18591
- Anne Simons Deas papers, ca. 1900.1
- Aqui Estamos1
- Avery Normal Institute1
- Benjamin H. Rutledge Family Papers, 1675-18671
- Berry Family Papers, 1767-19291
- Captain William Boykin Lyles Estate Record Ledger1
- Catherine M. McCottry, M.D. Papers1
- Certificate of citizenship, 1871 - McCormick, John, fl. 18711
- Charleston Bible Society Records, 1815-20101
- Church Session Books Excerpts, 1816-1901.1