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Collection
- Robert F. W. Allston papers, 1817-18681
- Robert Gilmor Travel Account1
- Roper Hospital Digital Collections1
- Rose P. Ravenel Family Papers, 1857-ca. 1920.1
- Roslin Plantation Journal, 1813-18151
- Samuel Miller apprenticeship indenture, 18051
- Samuel Pope, Seaman's Protection Certificate, 18201
- Sanitary Survey of the Rural Portion of Charleston County, 19211
- Sarah Campbell Allan, M.D. Papers 1895-19531
- South Carolina Medical Association Oral History Collection1
- Springfield Plantation Journal,1831 - 18641
- Susan M.L. Wales Journal, 1887-18951
- The Black Whale, by Gabriel E. Manigault1
- The Church Register of the Salem Methodist Episcopal Church, South.1
- The Fundamental Constitutions of Carolina, 16691
- The Petition of the Inhabitants of the Parishes of St. Philip and St. Michael, 17801
- Trinity Episcopal Cathedral Archival Colletions1
- University of South Carolina. South Caroliniana Library1
- Vincent P. Lannie Collection, 1733-19741