- John Shaw Billings Scrapbook27
- Pawleys Island Civic Association27
- Circular Congregational Church Records, 1732-1796 (bulk 1800-1910s)24
- Greenwood County Library Photographs24
- Historic Southern Naturalists24
- Lanny and Sidney Palmer Collection23
- In Camp And At The Front, WW1 Selections, South Carolina Political Collections22
- South Carolina Bookmobiles Collection21
- John Hensel Photograph Collection18
- Charleston Earthquake 188617
- Henry William Ravenel Papers, 1739-193516
- Sargeant Studios16
- Carl Julien Collection15
- Georgetown County Museum Collection15
- Gordon R. Hennigar Pathology Museum Collection15
- Historic Meeting Minutes of Mullins, South Carolina15
- Augusta Baker Papers, 1911-199814
- Horry County Historical Society Photograph Collection14
- Williams, Chesnut, Manning Family Papers, 1682-192614
- Alexander McBeth Store Ledger, 179413