- Rabbi Jacob S. Raisin Papers18
- Charleston Firefighters Rosters, 1862-186416
- Cranston Family Papers, 1822-195916
- Henry William Ravenel Papers, 1739-193516
- Septima P. Clark Papers, ca. 1910-ca. 199016
- Cleveland L. Sellers, Jr. Papers, 1934 - 200315
- Susan Pringle Alston’s Receipts, 1891-192115
- Bacot Family Papers, 1752-197314
- American Revolution Records in the Discrete Manuscript Collection13
- Mamie E. Garvin Fields Papers, 1894 - 198713
- Anita Pollitzer Family Papers12
- Paul Hamilton Papers12
- Thomas J. Tobias papers, ca. 1790-197012
- Adger Family Papers, 1813-193211
- Craft and Crum Families, 1780-200711
- Town of Sullivan's Island Historic Meeting Minutes11
- The Citadel and the American Civil War10
- William Drayton Rutherford Papers10
- Anna E. Alston Albums, 1880-19219
- Gabriel Manigault Journal, 1774-17848