- Frederick E. Kredel, M.D. Papers, 1925-19804
- J. Marion Sims Letters4
- Nathaniel Russell Middleton Papers, 1823-18814
- American Federation of Musicians Local 502 records, 1911-19143
- Bowman Family Papers, 1835-18923
- Charleston Slave Passes3
- Charleston Year Book, 19363
- Horlbeck Brothers Records, 1824-18603
- McLeod Family Papers, 1873-1990 (bulk 1900-1965)3
- Pinckney Family Papers, 1703-18473
- Sarah Campbell Allan, M.D. Papers 1895-19523
- South Carolina Historical Society Manuscripts3
- Temple Sinai (Sumter, S.C.) Records3
- William Tennent III Journal and Album3
- Charleston City Directories2
- Charleston Iron Works records, 19072
- Emily Clarkson Ball Grainger Family Papers, 1839-1962 (bulk 1926-1950)2
- Ethelyn Murray Parker Papers2
- Friendly Moralist Society Records, 1841-18562
- Helen Evangeline Banks Harrison papers (circa 1850 - 1985)2