- American Federation of Musicians Local 502 records, 1911-19143
- American Revolution Records in the Discrete Manuscript Collection28
- Angelica Singleton Van Buren Collection3
- Anita Pollitzer Family Papers13
- Anna D. Kelly Papers, 1930s - 19994
- Anna E. Alston Albums, 1880-192141
- Anna M.S. Wells Receipt Book10
- Anne Simons Deas papers, ca. 1900.1
- Aqui Estamos1
- Architect - George E. Walker79
- Armstrong Family Papers, 1900-193071
- Avery Normal Institute1
- Bacot Family Papers, 1752-197334
- Ball Family Papers, 1631-1895791
- Ball Family Papers, 1631-189637
- Barnwell Family Papers622
- Beautifying and Improving Greenville, S.C.51
- Benjamin H. Rutledge Family Papers, 1675-18671
- Berkeley County (S.C) Memories2
- Berkeley County (S.C.) Memories42