- Lazarus and Hirsch Family Papers23
- Modjeska Simkins: In Her Own Words23
- Periodic Reports to the Clemson University Board of Trustees23
- Chester County Historical Collection, 1739-199722
- Paul Hamilton Papers22
- Historical and Governing Records, 1841-192521
- Diary of Charles Drayton I, 1791-179820
- Lucas-Porcher Family Papers, 1827-197220
- Susan Pringle Alston’s Receipts, 1891-192120
- The Development of the Printed Page: 150 Examples of Handpress Printing and its Antecedents, ca. 1200 to 193719
- Buildings and Properties, 1841-193718
- City Year Books for Charleston, South Carolina, 1880-195118
- Mary Lamboll Thomas Beach Papers, 1822-189018
- Newton Plantation Collection18
- Book Lovers' Club, 1927 - 196917
- Erastus W. Everson Papers, 1837-189317
- John R. Beaty Letters17
- Charleston Firefighters Rosters, 1862-186416
- Cranston Family Papers, 1822-195916
- Slavery at South Carolina College, 1801-186516