- University of South Carolina Reconstruction Records16
- Warren Hubert Moise Letters, 1933-193915
- Samuel Badger Papers, 1767-177314
- South Carolina Dental Association Records14
- Anita Pollitzer Family Papers13
- J. Arthur Brown Papers, 1937 - 198813
- John West: In His Own Words12
- Trinity Episcopal Cathedral Archival Collections12
- Adger Family Papers, 1813-193211
- Craft and Crum Families, 1780-200711
- Hurricane Hugo Oral History Collection, 200911
- James Simons Papers, 1832-187911
- Letters to Alfred Wardlaw, 1857-186211
- Town of Sullivan's Island Historic Meeting Minutes11
- Woodward Manning Papers, 1771-190611
- Anna M.S. Wells Receipt Book10
- Charles Henry Meltzer Papers, 1839-194010
- Collection of Bishop Patrick Lynch Confederate Commissioner Papers, 1864-186510
- Lutheran Theological Southern Seminary Collection10
- Marguerite Andell Collection, 1919-194610