Collection
- Downtown Greenville 2
- Dr. Elizabeth Clarice Hall Collection9
- Drayton Family Papers, 1837-186965
- Drayton Papers, 1701-200431
- Drayton family papers, 1837-18691
- Due West Female College Photograph Collection31
- Dunean Mill42
- E. Don Herd Photograph Collection1,112
- E. E. Burson Photograph Collection250
- E.D.E.N. Southworth Collection44
- E.T. Start Photograph Collection213
- Early California Scrapbooks1
- Early History of Columbia College144
- Echo Valley12
- Edgewood School Yearbooks6
- Edisto Island Historic Preservation Society Oral Histories6
- Edmondston-Alston Family Letters and Paper Materials, 1782-19191,320
- Edmondston-Alston Photograph Collection33
- Edwin A. Harleston Collection3
- Edwin E. Gordon Papers3