- Bonds Conway Papers, 1763-1907125
- Book Lovers' Club, 1927 - 196940
- Bookmobiles112
- Bookmobiles 3
- Books and Pamphlets160
- Bowman Family Papers, 1835-18924
- Brad Lephew WWII Collection12
- Bradford Scrapbook Collection56
- Brandon Mill49
- Brandon Mill Ledger280
- Bratton Family Papers, 1764-1983282
- Bratton Family Papers, 1764-1983.1,261
- Bratton Family Papers, 1764-19841
- Briggs v. Elliott43
- Brookgreen Gardens Collection700
- Buildings and Properties, 1841-193749
- Bull Family of Chick Springs26
- Burton L. Padoll Papers, 1957-2009110
- Business Guide of Charleston, S.C.1
- Businesses of Greenville County298