- Literary Annuals1
- McBee Sons & Company Store Ledger Book, 1846-18611
- Minutes of the Annual Conferences of the Baptist, Episcopal, Lutheran, Methodist, and Presbyterian Churches in South Carolina, 1785-19203
- Mulberry Plantation Journals, 1853-1908 (bulk 1853-1889)1
- Porcher Family Papers, 1740-1967 (bulk 19th century)1
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library2
- Richmond Plantation Journal, 1859-18601
- Ron Swain Map Collection1
- Russell Maxey Photograph Collection1
- Shakespeare First Folio Teaching Resources1
- South Carolina Baptist Church Records92
- South Carolina Fall Line Collection1
- South Caroliniana Library Map Collection3
- St. Paul's Episcopal Church records, 1819-19711
- The American Revolution in South Carolina1
- Thomas J. Tobias papers, ca. 1790-19701
- University of South Carolina Student Exams, 1854 - 19174
- Vera Nathans Semel Papers, 1830-19851
- Waring Historical Library Inaugural Theses20
- William A. Rosenthall Judaica Collection - Prints and Photographs11