Collection
- Herald-Journal Willis Collection7
- Home Movies from Moving Image Research Collections3
- James Calvin Hemphill, Sr. Architectural Collection1
- John Shaw Billings Scrapbook1
- Joseph A. DeLaine Papers2
- Lander University Yearbooks1
- Lutheran Theological Southern Seminary Collection1
- MUSC Anatomy Class and Dissection Room Photographs1
- MUSC College of Medicine Class Photos1
- MUSC College of Nursing Class Photos1
- Maps of Columbia and Richland County1
- McLeod Family Papers, 1873-1990 (bulk 1900-1965)1
- Midlands Memories4
- Piedmont Image Collection480
- Robert B. Ariail Collection of Historical Astronomy1
- Sanborn Fire Insurance Maps of South Carolina12
- South Carolina Baptist Church Records51
- South Carolina Fall Line Collection1
- South Carolina Postcards9
- South Carolina Railroad Photograph Collection1