- Clemson Commencement Program1
- Clemson University Board of Trustees Minutes and Reports622
- Clemson University Faculty Manuals38
- Cleveland L. Sellers, Jr. Papers, 1934 - 2003714
- Cohen, Emanuel, Moses, Seixas Family Papers4
- Colleton County Memorial Library Bookmobile History2
- Cooperative Annual Reports26
- Early History of Columbia College97
- Erastus W. Everson Papers, 1837-18933
- Esau Jenkins Papers, 1963-2003143
- Ethelyn Murray Parker Papers34
- Eugene C. Hunt Papers, 1834 - 199486
- Fox Movietone News: The War Years204
- Francis Peyre Porcher Papers1
- Frederick E. Kredel, M.D. Papers, 1925-19801
- Fritz Hollings: In His Own Words4
- Greenville City Codes4
- Gussie Johnson Papers, 1940-200014
- Hampstead and Bethany Cemeteries53
- Helen Evangeline Banks Harrison papers (circa 1850 - 1985)18