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Collection
- Agricultural Society of South Carolina Visual Materials47
- Alice Ravenel Huger Smith Collection1
- Ansonborough Rehabilitation Project2
- Aqui Estamos52
- Avery Normal Institute182
- Beulah Glover Photograph Collection5
- C. Wayne Weart Apothecary Trade Cards, 1870-1920251
- C. Wayne Weart Pharmacy History Collection32
- Catherine M. McCottry, M.D. Papers10
- Charles Fraser's Sketchbook, 1796-1805114
- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.1,401
- Charleston Earthquake 1886137
- Charleston Souvenir Books2
- Chibbaro Stereograph Collection: 186u-1997420
- Civil War and Reconstruction Era Stereoscope Photographs of the Port Royal Region15
- Drayton Papers, 1701-200424
- Erastus W. Everson Papers, 1837-18931
- Ethelyn Murray Parker Papers19
- Frederick E. Kredel, M.D. Papers, 1925-19803
- George LaGrange Cook Photograph Collection99