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Collection
- University of South Carolina Reconstruction Records25
- Armstrong Family Papers, 1900-19304
- Ball Family Papers, 1631-18951
- Books and Pamphlets9
- Carolina Bands Collection31
- Catalog of the Collections of Minerals in the College of South Carolina1
- Edwin Hughes Collection18
- Fairfield County Manuscript Collection4
- Grimke family papers, 1678-19771
- Halley's Comet Project, 1985-19861
- Henry William Ravenel Papers, 1739-193525
- History of the University of South Carolina School of Medicine - Columbia1
- James and Marian Robinson Scrapbooks, 1935-19691
- Keziah Brevard Journal, 1860-18611
- Langdon Cheves Papers, 1777-18642
- Mamie E. Garvin Fields Papers, 1894 - 19871
- Modjeska Simkins: In Her Own Words18
- Paul Hamilton Papers2
- Pee Dee District Dental Society Records, 1933-19881
- Sarah Campbell Allan, M.D. Papers 1895-19522