- At Low Tide Oral Histories1
- At Low Tide Photographs1
- Azalea Festival of the Society of the Negro Spiritual, 19361
- Beulah Glover Photograph Collection1
- Bowman Family Papers, 1835-18921
- Bratton Family Papers, 1764-19841
- Call for Change1
- Carolina Bands Collection1
- Catherine M. McCottry, M.D. Papers1
- Certificate of citizenship, 1871 - McCormick, John, fl. 18711
- Charleston Year Book, 19371
- Charleston Year Book, 19381
- Chesnut Family Papers, 1741-19001
- City of Charleston Collection1
- Civil Rights Films from USC's Moving Image Research Collections1
- Cohen, Emanuel, Moses, Seixas Family Papers1
- Collected Receipts of William Butler of Greenville1
- Colleton County Memorial Library Map Collection1
- Color slides of South Carolina State Parks1
- Confederate Spartanburg1