- Alan Seeger, Le Poète de la Légion Étrangère1
- Ale boycott records, 18904
- Alexander Glennie Journal, 1831-18591
- Alexander Inglis Papers, 1782-1811 (bulk 1800-1802)2
- Alexander McBeth Store Ledger, 17941
- Alice Ravenel Huger Smith Collection2
- Allen University Digital Collections30
- Alliance for Full Acceptance records11
- Allston Family Papers, 1730-1901247
- American Federation of Musicians Local 502 records, 1911-19143
- Andrews Museum Collection187
- Angelica Singleton Van Buren Collection3
- Anna D. Kelly Papers, 1930s - 1999307
- Anne Simons Deas papers, ca. 1900.1
- Ansonborough Rehabilitation Project184
- Aqui Estamos9
- Architecture Publications1
- Armstrong Family Papers, 1900-1930128
- Art Work of Charleston1
- At Low Tide Oral Histories19