- YWCA of Greater Charleston, Inc., Records, 1906 - 200710
- Lonnie W. Fleming, Sr. Photograph Collection9
- Williams, Chesnut, Manning Family Papers, 1682-19269
- South Carolina Aerial Photograph Indexes, 1937-19898
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19957
- Furman Magazine7
- Inventory of S.C. Church Archives7
- John Henry McCray papers, 1929-19897
- William Drayton Rutherford Papers7
- South Carolina and World War II6
- The Marian Bruce Logan Collection of Civil Rights Activism, Personal Correspondence, 1945-19896
- Belle W. Baruch Collection5
- Greenville County Coroner Reports 5
- Historic Southern Naturalists5
- Photos from the Records of The Historic Preservation Planner, BCD-COG5
- South Carolina and the Civil War5
- WPA Federal Writers' Project on African American Life in South Carolina5
- William Lynch Postcard Collection5
- Cleveland L. Sellers, Jr. Papers, 1934 - 20034
- History of the University of South Carolina School of Medicine - Columbia4