Collection
- Ball Family Papers, 1631-18951
- Belle W. Baruch Collection1
- Brookgreen Gardens Collection1
- Civil Rights Films from Moving Image Research Collections1
- Civil War Correspondence1
- David Wyatt Aiken Papers, 1849-19761
- Drayton Papers, 1701-20041
- Edisto Island Historic Preservation Society Oral Histories1
- Friendly Moralist Society Records, 1841-18561
- From the Kitchen Drawer and Cupboard: The Jerred Metz Collection of Manufacturers' Recipe and Advertisement Booklets 1902-19501
- Georgetown County Digital Library1
- Gertrude Sanford Legendre Papers, 1844-19961
- Harry and William Birch Collection1
- Harvey Gantt and the Integration of Clemson University1
- History of the University of South Carolina School of Medicine - Columbia1
- J. Arthur Brown Papers, 1937 - 19881
- John Henry McCray papers, 1929-19891
- Local Television Newsfilm Collections1
- Midlands Memories1
- Papers of the Cox and Chesnut Families, 1792-18581