- Gertrude Sanford Legendre Papers, 1844-199613
- South Carolina Historical Records Survey Collection13
- United States Marine Corps Films13
- George LaGrange Cook Photograph Collection12
- Historic Southern Naturalists12
- The Charleston Oral History Program11
- William Lynch Postcard Collection11
- Georgetown County Museum Collection10
- South Carolina Children's Library Services Collection10
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library9
- Summerville Museum and Research Center Pamphlet Collection9
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19958
- Henry William Ravenel Papers, 1739-19358
- Papers of the Cox and Chesnut Families, 1792-18588
- Richland Library Archives8
- William D. Workman, Jr. Papers Photographs8
- Cleveland L. Sellers, Jr. Papers, 1934 - 20037
- Loose Papers of the Summerville Museum and Research Center7
- South Carolina LGBTQ Oral Histories, Archives, and Outreach7
- Henry William Ravenel, Plants and Planter6