- In Camp And At The Front, WW1 Selections, South Carolina Political Collections30
- South Carolina LGBTQ Oral Histories, Archives, and Outreach30
- Allston Family Papers, 1730-190129
- Minutes of the Annual Conferences of the Baptist, Episcopal, Lutheran, Methodist, and Presbyterian Churches in South Carolina, 1785-192029
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library25
- At Low Tide Photographs24
- Brookgreen Gardens Collection24
- Eleanor Parsons Moody Collection24
- Avery Normal Institute22
- Joseph A. DeLaine Papers22
- Thomas Benton Brooks Papers22
- Senator Burnet R. Maybank Papers, 1914-197321
- John Hensel Photograph Collection20
- Andrews Museum Collection19
- John Henry McCray papers, 1929-198919
- Midlands Memories19
- James Glen Papers17
- Bernice Robinson Papers, 1920-198916
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-199516
- City Directories of South Carolina16