- Henry William Ravenel Papers, 1739-19351
- In Camp And At The Front, WW1 Selections, South Carolina Political Collections1
- Isaiah DeQuincey Newman Papers1
- James E. Campbell papers, 1930-20091
- John Hensel Photograph Collection1
- Keystone View Company Lantern Slides, 1892-19121
- Lonnie W. Fleming, Sr. Photograph Collection1
- Mabel Payne Photograph Collection1
- Philip Simmons Collection1
- Postcards of the Midlands1
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library1
- Russell Maxey Photograph Collection1
- Septima P. Clark Papers, ca. 1910-ca. 19901
- South Carolina Fall Line Collection1
- South Carolina in Postcards1
- The American Revolution in South Carolina1
- The State Newspaper Photograph Archive1
- William A. Rosenthall Judaica Collection - Postcards1
- William A. Rosenthall Judaica Collection - Prints and Photographs1
- William D. Workman, Jr. Papers Photographs1