Collection
- Papers of the Cox and Chesnut Families, 1792-1858124
- University of South Carolina Buildings and Grounds121
- Diaries106
- Temple Sinai (Sumter, S.C.) Records104
- Jewish Heritage Collection Oral Histories103
- At Low Tide Videos101
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-199599
- Bernice Robinson Papers, 1920-198995
- South Carolina Library Buildings Collection95
- History of the University of South Carolina School of Medicine - Columbia94
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library94
- Greenville South Carolina Newspapers92
- Historical Newspapers92
- South Caroliniana Library Map Collection86
- Joseph A. DeLaine Papers82
- Cleveland L. Sellers, Jr. Papers, 1934 - 200378
- Beaumont E Newspaper Collection76
- G. Ross Roy Collection of Burnsiana and Scottish Literature74
- Fritz Hollings: In His Own Words72
- Brookgreen Gardens Collection69