- South Caroliniana Library Map Collection1,083
- Works Progress Administration photograph collection: South Carolina places : 193u-194u.1,069
- Photos from the Records of The Historic Preservation Planner, BCD-COG985
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library940
- Thomas Benton Brooks Papers932
- Postcards of the Midlands924
- Greenwood Mills Photograph Collection919
- John Henry McCray papers, 1929-1989912
- Midlands Memories901
- Gordon R. Hennigar Pathology Museum Collection900
- This is Charleston894
- William ("Bill") Saunders Papers, circa 1950 - 2004891
- Women's education in early 20th century Greenville878
- Cleveland L. Sellers, Jr. Papers, 1934 - 2003875
- Belle W. Baruch Collection854
- Lonnie W. Fleming, Sr. Photograph Collection818
- Ball Family Papers, 1631-1895798
- Tin Pan Alley Sheet Music Collection798
- Greenville Civic and Commercial Journal795
- Richard Furman and James C. Furman Collection791