Collection
- Edisto Island Historic Preservation Society Oral Histories1
- Eleanor Parsons Moody Collection1
- Equal Rights Amendment1
- Eric Crawford Oral Histories, 2007-20101
- Forgotten Books1
- From the Kitchen Drawer and Cupboard: The Jerred Metz Collection of Manufacturers' Recipe and Advertisement Booklets 1902-19501
- Gourdin Family Collection, 1707-19031
- Historic Southern Naturalists1
- Huger Family Papers, 1795-18971
- Illustrated Newspaper Clippings, 1840-19171
- Isaiah DeQuincey Newman Papers1
- J. Arthur Brown Papers, 1937 - 19881
- James Glen Papers1
- Jeffersonian Americana1
- Jimmy Cornelius Stone Collection1
- John Henry McCray papers, 1929-19891
- John McCrady Plats and Deeds Collection1
- Kinloch Gun Club1
- Lanny and Sidney Palmer Collection1
- MUSC College of Pharmacy Class Photos1