- Walter Pantovic Slavery and African American History Collection2
- Williams, Chesnut, Manning Family Papers, 1682-19262
- Allen University Digital Collections1
- Bicentennial Photograph Collection1
- City of Charleston Zoning Ordinances1
- Colleton County Memorial Library Bookmobile History1
- Dart Family Papers (1844-1945)1
- David Wyatt Aiken Papers, 1849-19761
- Diamond Fields of South Africa: Memoirs, Mines, and Minerals1
- Frederick E. Kredel, M.D. Papers, 1925-19801
- Gertrude Sanford Legendre Papers, 1844-19961
- Grimke family papers, 1678-19771
- Gussie Johnson Papers, 1940-20001
- Harry and William Birch Collection1
- Historic Southern Naturalists1
- Historical and Governing Records, 1841-19251
- Isaiah DeQuincey Newman Papers1
- Jimmy Price Studios1
- John West: In His Own Words1
- Joseph A. DeLaine Papers1