Collection
- Photographic Record of the Cooper River Bridge1
- Postcard Collection of Mullins, South Carolina1
- Richard L. Walker: In His Own Words1
- Robert McNair: In His Own Words1
- Ron Swain Map Collection1
- Roslin Plantation Journal, 1813-18151
- Samuel Lander Papers1
- Smith and Wells Papers, 1856-19071
- Solomon Blatt: In His Own Words1
- Somebody Had To Do It1
- South Caroliniana Library Map Collection1
- Spartanburg Regional Healthcare System Collection1
- Strom Thurmond Collection, Mss 1001
- Tarbox Family Photograph Collection1
- The WPA Week in National Defense1
- Town of Sullivan's Island Historic Meeting Minutes1
- Voice of an Island Oral Histories and Service Recordings, 2012-20131
- WPA Federal Writers' Project on African American Life in South Carolina1
- Walter S. McDonald Photograph Collection1
- William A. Rosenthall Judaica Collection - Prints and Photographs1