- Lutheran Church Records of South Carolina64
- New South Newspaper64
- Semaphore64
- Kahal Kadosh Beth Elohim Congregation Records63
- Bessie Norris Wofford collected funeral programs, 1957-199162
- City Year Books for Charleston, South Carolina, 1880-195162
- Paul Cross Papers, 1768-180361
- William Gravely Oral History Collection on the Lynching of Willie Earle61
- Cloe T.W. Greene Diaries59
- Henry William Ravenel, Plants and Planter59
- Thomas J. Tobias papers, ca. 1790-197056
- Harby, Moise, Levy, Moses, Davis Family Photographs55
- Oliver Hart papers, 1741-196154
- The Bonneville Collection: 19th Century Images of Native Americans and Soldiers in the American Mid-West54
- MUSC College of Medicine Class Photos53
- School Desegregation in the Southern and Border States53
- Converse Yearbooks52
- Grimke family papers, 1678-197749
- South Carolina Children's Library Services Collection49
- Elizabeth Pringle Diaries47