- Paul Cross Papers, 1768-180330
- James T. McCain Papers, 1957-197228
- Maxcy Gregg Papers, 1835-1888.28
- Oliver Hart papers, 1741-196125
- Briggs v. Elliott20
- Columbia Theater and Entertainment16
- Martha Elizabeth Cunningham Monteith Collection14
- Bratton Family Papers, 1764-198312
- Spartanburg County in World War I Collection11
- Williams Furniture Company Collection11
- World War I, Irvin Department of Rare Books and Special Collections11
- Thomas Family Collection10
- Modjeska Simkins: In Her Own Words9
- Bratton Family Papers, 1764-1983.8
- Gussie Johnson Papers, 1940-20008
- Isaac Samuel Leevy Papers, 1905-19738
- Robert McNair: In His Own Words7
- South Carolina Baptist Church Records7
- Ada Clare Papers, 1841-18646
- Butler Derrick: In His Own Words6