- Kahal Kadosh Beth Elohim Congregation Records1
- Keystone View Company Lantern Slides, 1892-1912218
- Lawrence Layden Scrapbook, 1941-194581
- Lazarus and Hirsch Family Papers43
- Lewis R. Gibbes Papers, 1800s-1893, 193713
- Lowcountry Tourism3
- Martha Mondschein Bauer Papers, 1940-200111
- Maynard Pearlstine Travel Albums and Sketches, 1936-200624
- Middleton Family Art Work, 1803-18671
- Moses Family Papers45
- Pearlstine-Strauss Family Papers130
- Pierrine Smith Byrd Papers, 1919-199113
- Pincus Kolender Papers, circa 1915-199620
- Rabbi Jacob S. Raisin Papers41
- Roy S. MacElwee Collection20
- Samuel Lord Hyde Photographs137
- Senator Burnet R. Maybank Papers, 1914-19731
- South Carolina Inter-State and West Indian Exposition, 1901-19022
- The Joseph Mordecai Hirschmann Collection197
- The Lithographs of Prentiss Taylor: a Catalogue Raisonne16