- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.1,401
- Charleston Earthquake 1886137
- Charleston Museum Earthquake Photographs203
- Charleston Museum Illustrated Newspapers Collection281
- Charleston Naval Shipyard Photographs819
- Charleston Souvenir Books2
- Charleston, S.C. Indelible Photographs1
- Chibbaro Stereograph Collection: 186u-1997420
- Civil War and Reconstruction Era Stereoscope Photographs of the Port Royal Region15
- Cleveland L. Sellers, Jr. Papers, 1934 - 200310
- College of Charleston Buildings and Grounds Photograph Collection1,059
- College of Charleston Scrapbooks and Photo Albums2
- College of Charleston Stereoscope Views1
- Craft and Crum Families, 1780-20075
- Dientje Krant Kalisky Adkins Photographs, 1938-199622
- Drayton Papers, 1701-200424
- Erastus W. Everson Papers, 1837-18931
- Ethelyn Murray Parker Papers19
- Frances A. Robb Photograph Album1
- Francine Ajzensztark Taylor Papers, circa 1913-198517