- South Carolina Library Buildings Collection11
- Catherine M. McCottry, M.D. Papers10
- Cleveland L. Sellers, Jr. Papers, 1934 - 200310
- Lewis R. Gibbes Papers, 1800s-1893, 19379
- MUSC College of Pharmacy Class Photos9
- Phosphates in South Carolina, 1870-18909
- William Martin Aiken Papers, 1878-19569
- MUSC College of Graduate Studies Class Photos7
- Postcards of the Midlands7
- South Carolina Aerial Photograph Indexes, 1937-19897
- L.A. Hall Civil War and Reconstruction Eras Stereoscopic Images6
- Rabbi Jacob S. Raisin Papers6
- South Carolina Bookmobiles Collection6
- South Carolina and the Civil War6
- Beulah Glover Photograph Collection5
- Craft and Crum Families, 1780-20075
- Shadows of the Gullah Geechee5
- The Citadel Alumni War Veterans Collection5
- 1920s Charleston Scenes4
- Albert Simons Papers, 1908-19774