- L. Mendel Rivers Papers, 1940-19627
- Isaac Harby Family Papers6
- Harry Blas and Erika Stockfleth Blas Papers, circa 1910-circa 19805
- Vincent P. Lannie Collection, 1733-19745
- Eighteenth & Nineteenth Century Correspondence Collection4
- Nathaniel Russell Middleton Papers, 1823-18814
- Charleston Slave Passes3
- Charleston Year Book, 19363
- Senator Burnet R. Maybank Papers, 1914-19733
- Temple Sinai (Sumter, S.C.) Records3
- Cohen, Emanuel, Moses, Seixas Family Papers2
- Phillips Family Papers2
- Weston Family Papers, 1764-18552
- Charles Fraser Book of Precedents, 1800-18191
- Charleston and Savannah Railroad Records1
- Fairfield Plantation Papers1
- Frank Fisher Notes, 1882-19021
- Harby Academy Cashbook1
- Hebrew Benevolent Society Papers1
- Henry Laurens Account Book, 1766-17331