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Collection
- Langdon Cheves Papers, 1777-186454
- Ball Family Papers, 1631-189541
- Cranston Family Papers, 1822-195911
- Allston Family Papers, 1730-19019
- James Simons Papers, 1832-18798
- Bowman Family Papers, 1835-18923
- Emily Clarkson Ball Grainger Family Papers, 1839-1962 (bulk 1926-1950)2
- Horlbeck Brothers Records, 1824-18602
- Charleston Bible Society Records, 1815-20101
- Pringle-Garden Family Papers, 1701-18821
- Robert Heriot Correspondence, 17811
- Slave Records in the Discrete Manuscript Collection1
- Vanderhorst Family Papers, 1689-19421
- Woodward Manning Papers, 1771-19061