- Allston Family Papers, 1730-19014
- Heyward and Ferguson Family Papers, 1806-19234
- Cranston Family Papers, 1822-19593
- Inventory of S.C. Church Archives3
- The Development of the Printed Page: 150 Examples of Handpress Printing and its Antecedents, ca. 1200 to 19373
- William Ancrum Letter Book and Account Book3
- 'John Henry McCray papers, 1929-1989'2
- Armstrong Family Papers, 1900-19302
- Cleveland L. Sellers, Jr. Papers, 1934 - 20032
- G. Ross Roy Collection of Burnsiana and Scottish Literature2
- Horlbeck Brothers Records, 1824-18602
- Mary Motte Alston Pringle Receipt Book2
- McBee Sons & Company Store Ledger Book, 1846-18612
- Slave Records in the Discrete Manuscript Collection2
- St. Andrew's Society of Charleston Records, 1729-20012
- Strom Thurmond Collection, Mss 1002
- 4th South Carolina Regiment Order Book1
- Accounts and Estate Administration Books, 1824-18521
- Barnwell Family Papers1
- Berkeley County (S.C.) Memories1