- John Henry McCray papers, 1929-198921
- John Ravenel Estate Book, 1862-18701
- Journal of Robert Barnwell Plantations, 1838-18591
- Lazarus and Hirsch Family Papers1
- Loose Papers of the Summerville Museum and Research Center1
- Lydia Jane Waring Estate Book, 1840-18471
- Mamie E. Garvin Fields Papers, 1894 - 19871
- Middleton Papers, 1775-18151
- Newton Plantation Collection1
- Richard L. Johnson Medical Record Book, 1863-1864, 1867-18831
- Richmond Plantation Journal, 1859-18601
- Robert Gilmor Travel Account1
- Roslin Plantation Journal, 1813-18151
- Roswell T. Logan Journal, 1852-18651
- Sarah Campbell Allan, M.D. Papers 1895-19521
- Slavery at South Carolina College, 1801-18651
- South Carolina Historical Society Manuscripts1
- South Carolina Public Library History, 1930 - 19451
- South Caroliniana Library Map Collection1
- Springfield Plantation Journal,1831 - 18641