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Collection
- Ball Family Papers, 1631-18952
- Barnwell Family Papers2
- Charleston Museum Collection of Revolutionary War Letters1
- Civic Services Committee Papers21
- Drayton Papers, 1701-20041
- Edmondston-Alston Family Letters and Paper Materials, 1782-19191
- Eliza Pinckney Receipt Book1
- Family Bible Records2
- Gertrude Sanford Legendre Papers, 1844-19963
- Grimke family papers, 1678-19771
- Henry William Ravenel Papers, 1739-193511
- Heyward and Ferguson Family Papers, 1806-19232
- Historic Southern Naturalists1
- John West: In His Own Words1
- Lynch Family Letters, 1858-18661
- MUSC College of Dental Medicine Oral History Project, 20115
- Malloy Family Papers, 1861-19071
- Mary Motte Alston Pringle Receipt Book2
- Papers of the Cox and Chesnut Families, 1792-18581
- Roslin Plantation Journal, 1813-18151