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Collection
- Civic Services Committee Papers133
- The American Revolution in South Carolina11
- Grimke family papers, 1678-19778
- Wilkinson-Keith Family Papers5
- Frederick E. Kredel, M.D. Papers, 1925-19804
- South Carolina and the Civil War4
- Horace Gilbert Smithy, Jr., M.D. Papers3
- James Glen Papers3
- Slave Records in the Discrete Manuscript Collection3
- William ("Bill") Saunders Papers, circa 1950 - 20043
- William Drayton Rutherford Papers3
- Halley's Comet Project, 1985-19862
- Malloy Family Papers, 1861-19072
- South Carolina Historical Records Survey Collection2
- St. Paul's Episcopal Church records, 1819-19712
- University of South Carolina Student Exams, 1854 - 19172
- Chesnut Family Papers, 1741-19001
- Collected Papers of the Holland Family of Greenville County1
- Cote Bas and Mepkin Plantations Journals, 1865-18771
- Eighteenth & Nineteenth Century Correspondence Collection1