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Collection
- James W. Colbert, Jr., MD, Oral History Project, 20095
- Isaiah Bennett Papers, ca. 1932-20024
- Strom Thurmond Collection, Mss 1004
- Grimke family papers, 1678-19772
- Pierrine Smith Byrd Papers, 1919-19912
- Civic Services Committee Papers1
- Edwin Hughes Collection1
- Historic Southern Naturalists1
- History of the Charleston Fire Department, 19531
- Lynch Family Letters, 1858-18661
- Mamie E. Garvin Fields Papers, 1894 - 19871
- Mills Family of Greenville1
- Rabbi Jacob S. Raisin Papers1
- South Carolina Dental Association Records1
- South Carolina and the Civil War1
- The American Revolution in South Carolina1
- Wilkinson-Keith Family Papers1
- William ("Bill") Saunders Papers, circa 1950 - 20041
- William Drayton Rutherford Papers1
- YWCA of Greater Charleston, Inc., Records, 1906 - 20071