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Collection
- McLeod Family Papers, 1873-1990 (bulk 1900-1965)56
- Ball Family Papers, 1631-189552
- John McCrady Plats and Deeds Collection12
- Slave Records in the Discrete Manuscript Collection10
- Langdon Cheves Papers, 1777-18648
- Allston Family Papers, 1730-19014
- Drayton Family Papers, 1837-18694
- Adger Family Papers, 1813-19323
- Agricultural Society of South Carolina Visual Materials3
- Bacot Family Papers, 1752-19732
- Cranston Family Papers, 1822-19592
- Emily Clarkson Ball Grainger Family Papers, 1839-1962 (bulk 1926-1950)2
- James Simons Papers, 1832-18792
- Anita Pollitzer Family Papers1
- Drayton family papers, 1837-18691
- General Orders of William Moultrie and Benjamin Lincoln, 17791
- Hutson Lee Papers, 1858-18651
- Invoice of rice sales for Anthony Clarkson, 1762 Oct. 301
- Mary Lamboll Thomas Beach Papers, 1822-18901
- Pringle-Garden Family Papers, 1701-18821