Collection
- David Wyatt Aiken Papers, 1849-1976177
- De priscorum proprietate verborum1
- De verborum significatione1
- De victoria Christi contra Antichristum1
- DeBerniere Family Papers, 1790-1930 (bulk 1790-1860)1
- Deas Family Papers and Research, 1766-19762
- Delbert Claire Brandt Collection91
- Dialogorum libri quattuor1
- Diamond Fields of South Africa: Memoirs, Mines, and Minerals7
- Diaries110
- Diary and Account Book of Rene Ravenel and Henry Ravenel, 1731-186032
- Diary of Charles Drayton I, 1791-179820
- Dientje Krant Kalisky Adkins Photographs, 1938-199622
- Digital Collection (Relation)1
- Dill Family Collection11
- Dirleton Plantation Memorandum Book, 1859-19281
- Documentation for the People: Celebrating 125 Years as a Federal Depository Library15
- Documenting the African American Experience at Clemson195
- Dorchester: Our Homes - Our people - Our Story4
- Downtown Greenville460