- Housworth Stereographs Collection18
- Inventory of S.C. Church Archives44
- Jewish Heritage Collection Oral Histories5
- John Shaw Billings Scrapbook862
- Joseph E. Winter Photograph Collection3
- Kenneth Frederick Marsh Photograph Collection5
- L. Mendel Rivers Papers, 1940-19621
- Langdon Cheves Papers, 1777-18641
- M. Hayes Mizell Papers2
- Mamie E. Garvin Fields Papers, 1894 - 19871
- Minutes of the Annual Conferences of the Baptist, Episcopal, Lutheran, Methodist, and Presbyterian Churches in South Carolina, 1785-19205
- Postcards of the Midlands2
- Primary Sources for K-12, Pilot Project9
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library7
- Richard Furman and James C. Furman Collection1
- Sanborn Fire Insurance Maps of South Carolina27
- South Carolina Aerial Photograph Indexes, 1937-19898
- South Carolina Baptist Church Records4
- South Carolina Bookmobiles Collection9
- South Carolina Children's Library Services Collection1