Collection
- South Carolina Inter-State and West Indian Exposition, 1901-190212
- South Carolina LGBTQ Oral Histories, Archives, and Outreach64
- South Carolina Library Association Digital Collection4
- South Carolina Library Buildings Collection11
- South Carolina Medical Association Oral History Collection18
- South Carolina Oyster Industry: A History1
- South Carolina Pamphlets5
- South Carolina Public Library History, 1930 - 19451
- South Carolina Railroad Photograph Collection17
- South Carolina State Parks Civilian Conservation Corps Architectural Plans143
- South Carolina and the Civil War308
- South Caroliniana Library Map Collection158
- South Caroliniana Pamphlet Collection2
- Southeast region sites129
- St. Andrew's Society of Charleston Records, 1729-2001117
- Stereographic Views of South Carolina86
- Strom Thurmond Collection, Mss 1002
- Sullivan's Island Oral History Collection14
- Summerville Museum and Research Center Pamphlet Collection4
- Susan Pringle Alston’s Receipts, 1891-1921230